HFE FISH Probe
The HFE FISH probe is designed to hybridize to the HFE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HFE-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| HFE-20-RE | 20 (40 μL) | 200 μL |  |
|
| HFE-20-GO | 20 (40 μL) | 200 μL |  |
|
| HFE-20-GR | 20 (40 μL) | 200 μL |  |
|
| HFE-20-AQ | 20 (40 μL) | 200 μL |  |
|
| HFE-20-DIG | 20 (40 μL) | 200 μL |  |
|
| HFE-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HFE
Gene Name: Hemochromatosis
Chromosome: CHR6: 26087508-26095469
Locus: 6p22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: HFE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HFE-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping