HEXA FISH Probe
The HEXA FISH probe is designed to hybridize to the HEXA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HEXA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-RE | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-GO | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-GR | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-AQ | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-DIG | 20 (40 μL) | 200 μL |  |
|
| HEXA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: HEXA
Gene Name: Hexosaminidase Subunit Alpha
Chromosome: CHR15: 72635777-72668520
Locus: 15q23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: HEXA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HEXA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping