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HEXA FISH Probe

The HEXA FISH probe is designed to hybridize to the HEXA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
HEXA-20-OR  (Standard Design) 20 (40 μL) 200 μL
HEXA-20-RE 20 (40 μL) 200 μL
HEXA-20-GO 20 (40 μL) 200 μL
HEXA-20-GR 20 (40 μL) 200 μL
HEXA-20-AQ 20 (40 μL) 200 μL
HEXA-20-DIG 20 (40 μL) 200 μL
HEXA-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Gene Details

Gene Symbol: HEXA

Gene Name: Hexosaminidase Subunit Alpha

Chromosome: CHR15: 72635777-72668520

Locus: 15q23

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: HEXA FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: HEXA-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping