HERPUD1 FISH Probe
The HERPUD1 FISH probe is designed to hybridize to the HERPUD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HERPUD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-RE | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-GO | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-GR | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| HERPUD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
Gene Details
Gene Symbol: HERPUD1
Gene Name: Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1
Chromosome: CHR16: 56965747-56977793
Locus: 16q13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HERPUD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HERPUD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping