HEL-S-281 FISH Probe
The HEL-S-281 FISH probe is designed to hybridize to the HEL-S-281 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LDHB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LDHB-20-RE | 20 (40 μL) | 200 μL |  |
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| LDHB-20-GO | 20 (40 μL) | 200 μL |  |
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| LDHB-20-GR | 20 (40 μL) | 200 μL |  |
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| LDHB-20-AQ | 20 (40 μL) | 200 μL |  |
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| LDHB-20-DIG | 20 (40 μL) | 200 μL |  |
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| LDHB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: LDHB
Gene Name: Lactate Dehydrogenase B
Chromosome: CHR12: 21788274-21810789
Locus: 12p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HEL-S-281 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LDHB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping