HEBM1 FISH Probe
The HEBM1 FISH probe is designed to hybridize to the HEBM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ROCK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-RE | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-GO | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-GR | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ROCK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: ROCK1
Gene Name: Rho Associated Coiled-coil Containing Protein Kinase 1
Chromosome: CHR18: 18529702-18691812
Locus: 18q11.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HEBM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ROCK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping