HDHPR FISH Probe
The HDHPR FISH probe is designed to hybridize to the HDHPR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| QDPR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| QDPR-20-RE | 20 (40 μL) | 200 μL |  |
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| QDPR-20-GO | 20 (40 μL) | 200 μL |  |
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| QDPR-20-GR | 20 (40 μL) | 200 μL |  |
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| QDPR-20-AQ | 20 (40 μL) | 200 μL |  |
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| QDPR-20-DIG | 20 (40 μL) | 200 μL |  |
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| QDPR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: QDPR
Gene Name: Quinoid Dihydropteridine Reductase
Chromosome: CHR4: 17488015-17513857
Locus: 4p15.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HDHPR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: QDPR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping