HD5 FISH Probe
The HD5 FISH probe is designed to hybridize to the HD5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HDAC5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-RE | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-GO | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-GR | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-AQ | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-DIG | 20 (40 μL) | 200 μL |  |
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| HDAC5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HDAC5
Gene Name: Histone Deacetylase 5
Chromosome: CHR17: 42154120-42201014
Locus: 17q21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HD5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HDAC5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping