HCDCREL-1 FISH Probe
The HCDCREL-1 FISH probe is designed to hybridize to the HCDCREL-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEPT5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-RE | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-GO | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-GR | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-AQ | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-DIG | 20 (40 μL) | 200 μL |  |
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| SEPT5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: SEPT5
Gene Name: Septin 5
Chromosome: CHR22: 19701986-19710845
Locus: 22q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HCDCREL-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SEPT5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping