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HC10-II FISH Probe

The HC10-II FISH probe is designed to hybridize to the HC10-II gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PSMB3-20-OR  (Standard Design) 20 (40 μL) 200 μL
PSMB3-20-RE 20 (40 μL) 200 μL
PSMB3-20-GO 20 (40 μL) 200 μL
PSMB3-20-GR 20 (40 μL) 200 μL
PSMB3-20-AQ 20 (40 μL) 200 μL
PSMB3-20-DIG 20 (40 μL) 200 μL
PSMB3-20-BIO 20 (40 μL) 200 μL

Gene Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]

Gene Details

Gene Symbol: PSMB3

Gene Name: Proteasome Subunit Beta 3

Chromosome: CHR17: 36909001-36920478

Locus: 17q12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HC10-II FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PSMB3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping