HBGR FISH Probe
The HBGR FISH probe is designed to hybridize to the HBGR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HBG1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HBG1-20-RE | 20 (40 μL) | 200 μL |  |
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| HBG1-20-GO | 20 (40 μL) | 200 μL |  |
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| HBG1-20-GR | 20 (40 μL) | 200 μL |  |
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| HBG1-20-AQ | 20 (40 μL) | 200 μL |  |
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| HBG1-20-DIG | 20 (40 μL) | 200 μL |  |
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| HBG1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HBG1
Gene Name: Hemoglobin Subunit Gamma 1
Chromosome: CHR11: 5269501-5271087
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HBGR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HBG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping