HBB-HS-111 FISH Probe
The HBB-HS-111 FISH probe is designed to hybridize to the HBB-HS-111 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HBB-HS-111-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-RE | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-GO | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-GR | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-AQ | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-DIG | 20 (40 μL) | 200 μL | ||
HBB-HS-111-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This element represents a DNase I hypersensitive site located approximately 111 kb upstream of the HBE1 (hemoglobin, epsilon 1) gene in the beta-globin gene cluster. Chromosome conformation capture assays show that the orthologous mouse hypersensitive site is an integral part of the beta-globin active chromatin hub in erythroid cells, where it undergoes looping interactions with 3'HS1, which is located downstream of the beta-globin gene cluster, and this folding further enables interactions between the beta-globin locus control region (LCR) and active beta-globin gene promoters. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: HBB-HS-111
Gene Name: Beta-globin Hypersensitive Site -111
Locus: 11p15
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HBB-HS-111 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HBB-HS-111-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping