HAMP FISH Probe
The HAMP FISH probe is designed to hybridize to the HAMP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HAMP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HAMP-20-RE | 20 (40 μL) | 200 μL |  |
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| HAMP-20-GO | 20 (40 μL) | 200 μL |  |
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| HAMP-20-GR | 20 (40 μL) | 200 μL |  |
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| HAMP-20-AQ | 20 (40 μL) | 200 μL |  |
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| HAMP-20-DIG | 20 (40 μL) | 200 μL |  |
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| HAMP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: HAMP
Gene Name: Hepcidin Antimicrobial Peptide
Chromosome: CHR19: 35773409-35776045
Locus: 19q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HAMP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HAMP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping