The HAAO FISH probe is designed to hybridize to the HAAO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
HAAO-20-OR  (Standard Design) 20 (40 μL) 200 μL
HAAO-20-RE 20 (40 μL) 200 μL
HAAO-20-GO 20 (40 μL) 200 μL
HAAO-20-GR 20 (40 μL) 200 μL
HAAO-20-AQ 20 (40 μL) 200 μL
HAAO-20-DIG 20 (40 μL) 200 μL
HAAO-20-BIO 20 (40 μL) 200 μL

Gene Summary

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: HAAO

Gene Name: 3-hydroxyanthranilate 3,4-dioxygenase

Chromosome: CHR2: 42994228-43019751

Locus: 2p21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: HAAO FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL


Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping