HA2B FISH Probe
The HA2B FISH probe is designed to hybridize to the HA2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PSMB8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-RE | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-GO | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-GR | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-AQ | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-DIG | 20 (40 μL) | 200 μL |  |
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| PSMB8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PSMB8
Gene Name: Proteasome Subunit Beta 8
Chromosome: CHR6_cox_hap2: 4253021-4257240
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HA2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSMB8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping