H4-III FISH Probe
The H4-III FISH probe is designed to hybridize to the H4-III gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HIST2H4B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-RE | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-GO | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-GR | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-AQ | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-DIG | 20 (40 μL) | 200 μL |  |
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| HIST2H4B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: HIST2H4B
Gene Name: Histone Cluster 2 H4 Family Member B
Chromosome: CHR1: 149832329-149832725
Locus: 1q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: H4-III FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HIST2H4B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping