H174 FISH Probe
The H174 FISH probe is designed to hybridize to the H174 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CXCL11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-RE | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-GO | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-GR | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-AQ | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-DIG | 20 (40 μL) | 200 μL |  |
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| CXCL11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: CXCL11
Gene Name: C-X-C Motif Chemokine Ligand 11
Chromosome: CHR4: 76954839-76957350
Locus: 4q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: H174 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CXCL11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping