GYPB Break Apart FISH Probe
Empire Genomics’ GYPB Break Apart FISH Probe is designed to flank the GYPB gene and is typically used for detecting GYPB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GYPBBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GYPBBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GYPBBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GYPBBA-20-GORE | 20 (40 μL) | 200 μL |
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| GYPBBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GYPBBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GYPBBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GYPBBA-20-REGO | 20 (40 μL) | 200 μL |
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| GYPBBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: GYPB
Gene Name: Glycophorin B (MNS Blood Group)
Chromosome: CHR4: 144917256-144940496
Locus: 4q31.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GYPB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GYPB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping