GTF2A2 FISH Probe
The GTF2A2 FISH probe is designed to hybridize to the GTF2A2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GTF2A2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-RE | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-GO | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-GR | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-AQ | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-DIG | 20 (40 μL) | 200 μL |  |
|
| GTF2A2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008]
Gene Details
Gene Symbol: GTF2A2
Gene Name: General Transcription Factor IIA Subunit 2
Chromosome: CHR15: 59930260-59949737
Locus: 15q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GTF2A2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GTF2A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping