GSTM1 FISH Probe
The GSTM1 FISH probe is designed to hybridize to the GSTM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GSTM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-RE | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-GO | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-GR | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| GSTM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GSTM1
Gene Name: Glutathione S-transferase Mu 1
Chromosome: CHR1: 110230417-110236367
Locus: 1p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GSTM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GSTM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping