GSTA3 FISH Probe
The GSTA3 FISH probe is designed to hybridize to the GSTA3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GSTA3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-RE | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-GO | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-GR | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-AQ | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-DIG | 20 (40 μL) | 200 μL |  |
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| GSTA3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GSTA3
Gene Name: Glutathione S-transferase Alpha 3
Chromosome: CHR6: 52761438-52774496
Locus: 6p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GSTA3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GSTA3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping