GSAP Break Apart FISH Probe
Empire Genomics’ GSAP Break Apart FISH Probe is designed to flank the GSAP gene and is typically used for detecting GSAP rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSAPBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSAPBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GSAPBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GSAPBA-20-GORE | 20 (40 μL) | 200 μL |
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| GSAPBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GSAPBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GSAPBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GSAPBA-20-REGO | 20 (40 μL) | 200 μL |
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| GSAPBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: GSAP
Gene Name: Gamma-secretase Activating Protein
Chromosome: CHR7: 77416428-77310750
Locus: 7q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GSAP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GSAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping