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GS1-358P8.4 FISH Probe

The GS1-358P8.4 FISH probe is designed to hybridize to the GS1-358P8.4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PDK3-20-OR  (Standard Design) 20 (40 μL) 200 μL
PDK3-20-RE 20 (40 μL) 200 μL
PDK3-20-GO 20 (40 μL) 200 μL
PDK3-20-GR 20 (40 μL) 200 μL
PDK3-20-AQ 20 (40 μL) 200 μL
PDK3-20-DIG 20 (40 μL) 200 μL
PDK3-20-BIO 20 (40 μL) 200 μL

Gene Summary

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Gene Details

Gene Symbol: PDK3

Gene Name: Pyruvate Dehydrogenase Kinase 3

Chromosome: CHRX: 24483343-24568583

Locus: Xp22.11

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GS1-358P8.4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PDK3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping