GRN FISH Probe
The GRN FISH probe is designed to hybridize to the GRN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRN-20-RE | 20 (40 μL) | 200 μL |  |
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| GRN-20-GO | 20 (40 μL) | 200 μL |  |
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| GRN-20-GR | 20 (40 μL) | 200 μL |  |
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| GRN-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRN-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GRN
Gene Name: Granulin Precursor
Chromosome: CHR17: 42422490-42430470
Locus: 17q21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping