GRM6 Break Apart FISH Probe
Empire Genomics’ GRM6 Break Apart FISH Probe is designed to flank the GRM6 gene and is typically used for detecting GRM6 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRM6BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRM6BA-20-AQOR | 20 (40 μL) | 200 μL |
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| GRM6BA-20-GOGR | 20 (40 μL) | 200 μL |
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| GRM6BA-20-GORE | 20 (40 μL) | 200 μL |
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| GRM6BA-20-GRGO | 20 (40 μL) | 200 μL |
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| GRM6BA-20-GRRE | 20 (40 μL) | 200 μL |
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| GRM6BA-20-ORGR | 20 (40 μL) | 200 μL |
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| GRM6BA-20-REGO | 20 (40 μL) | 200 μL |
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| GRM6BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: GRM6
Gene Name: Glutamate Metabotropic Receptor 6
Chromosome: CHR5: 178405329-178422124
Locus: 5q35.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRM6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRM6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping