GRM2 FISH Probe
The GRM2 FISH probe is designed to hybridize to the GRM2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRM2-20-RE | 20 (40 μL) | 200 μL |  |
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| GRM2-20-GO | 20 (40 μL) | 200 μL |  |
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| GRM2-20-GR | 20 (40 μL) | 200 μL |  |
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| GRM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: GRM2
Gene Name: Glutamate Metabotropic Receptor 2
Chromosome: CHR3: 51741080-51752625
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping