GRIP-1 FISH Probe
The GRIP-1 FISH probe is designed to hybridize to the GRIP-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NCOA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-RE | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-GO | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-GR | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NCOA2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: NCOA2
Gene Name: Nuclear Receptor Coactivator 2
Chromosome: CHR8: 71024266-71316020
Locus: 8q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRIP-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NCOA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping