GRF1 FISH Probe
The GRF1 FISH probe is designed to hybridize to the GRF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASGRF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-RE | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-GO | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-GR | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RASGRF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: RASGRF1
Gene Name: Ras Protein Specific Guanine Nucleotide Releasing Factor 1
Chromosome: CHR15: 79252288-79383215
Locus: 15q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASGRF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping