GRF-1 FISH Probe
The GRF-1 FISH probe is designed to hybridize to the GRF-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGAP35-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-AQ | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-DIG | 20 (40 μL) | 200 μL |  |
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| ARHGAP35-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ARHGAP35
Gene Name: Rho GTPase Activating Protein 35
Chromosome: CHR19: 47421932-47508333
Locus: 19q13.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRF-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARHGAP35-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping