GREM1 FISH Probe
The GREM1 FISH probe is designed to hybridize to the GREM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GREM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GREM1-20-RE | 20 (40 μL) | 200 μL |  |
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| GREM1-20-GO | 20 (40 μL) | 200 μL |  |
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| GREM1-20-GR | 20 (40 μL) | 200 μL |  |
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| GREM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| GREM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| GREM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: GREM1
Gene Name: Gremlin 1, DAN Family BMP Antagonist
Chromosome: CHR15: 33010204-33026870
Locus: 15q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GREM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GREM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping