GRAPL FISH Probe
The GRAPL FISH probe is designed to hybridize to the GRAPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRAP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRAP-20-RE | 20 (40 μL) | 200 μL |  |
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| GRAP-20-GO | 20 (40 μL) | 200 μL |  |
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| GRAP-20-GR | 20 (40 μL) | 200 μL |  |
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| GRAP-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRAP-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRAP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: GRAP
Gene Name: GRB2-related Adaptor Protein
Chromosome: CHR17: 18923989-18950336
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRAPL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping