GPV FISH Probe
The GPV FISH probe is designed to hybridize to the GPV gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GP5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GP5-20-RE | 20 (40 μL) | 200 μL |  |
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| GP5-20-GO | 20 (40 μL) | 200 μL |  |
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| GP5-20-GR | 20 (40 μL) | 200 μL |  |
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| GP5-20-AQ | 20 (40 μL) | 200 μL |  |
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| GP5-20-DIG | 20 (40 μL) | 200 μL |  |
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| GP5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: GP5
Gene Name: Glycoprotein V Platelet
Chromosome: CHR3: 194115549-194119995
Locus: 3q29
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GPV FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GP5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping