GPS-2 FISH Probe
The GPS-2 FISH probe is designed to hybridize to the GPS-2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GPS2-20-RE | 20 (40 μL) | 200 μL |  |
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| GPS2-20-GO | 20 (40 μL) | 200 μL |  |
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| GPS2-20-GR | 20 (40 μL) | 200 μL |  |
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| GPS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GPS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GPS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GPS2
Gene Name: G Protein Pathway Suppressor 2
Chromosome: CHR17: 7215977-7218658
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GPS-2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GPS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping