GP5 Break Apart FISH Probe
Empire Genomics’ GP5 Break Apart FISH Probe is designed to flank the GP5 gene and is typically used for detecting GP5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GP5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
GP5BA-20-AQOR | 20 (40 μL) | 200 μL | ||
GP5BA-20-GOGR | 20 (40 μL) | 200 μL | ||
GP5BA-20-GORE | 20 (40 μL) | 200 μL | ||
GP5BA-20-GRGO | 20 (40 μL) | 200 μL | ||
GP5BA-20-GRRE | 20 (40 μL) | 200 μL | ||
GP5BA-20-ORGR | 20 (40 μL) | 200 μL | ||
GP5BA-20-REGO | 20 (40 μL) | 200 μL | ||
GP5BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: GP5
Gene Name: Glycoprotein V Platelet
Chromosome: CHR3: 194115549-194119995
Locus: 3q29
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GP5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GP5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping