GP1B FISH Probe
The GP1B FISH probe is designed to hybridize to the GP1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GP1BA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-RE | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-GO | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-GR | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-AQ | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-DIG | 20 (40 μL) | 200 μL |  |
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| GP1BA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013]
Gene Details
Gene Symbol: GP1BA
Gene Name: Glycoprotein Ib Platelet Alpha Subunit
Chromosome: CHR17: 4835591-4838325
Locus: 17p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GP1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GP1BA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping