GNRHR Break Apart FISH Probe
Empire Genomics’ GNRHR Break Apart FISH Probe is designed to flank the GNRHR gene and is typically used for detecting GNRHR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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GNRHRBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-AQOR | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-GOGR | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-GORE | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-GRGO | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-GRRE | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-ORGR | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-REGO | 20 (40 μL) | 200 μL | ||
GNRHRBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GNRHR
Gene Name: Gonadotropin Releasing Hormone Receptor
Chromosome: CHR4: 68603098-68621804
Locus: 4q13.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNRHR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNRHR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping