GNPTA FISH Probe
The GNPTA FISH probe is designed to hybridize to the GNPTA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNPTAB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-RE | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-GO | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-GR | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-AQ | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-DIG | 20 (40 μL) | 200 μL |  |
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| GNPTAB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: GNPTAB
Gene Name: N-acetylglucosamine-1-phosphate Transferase Alpha And Beta Subunits
Chromosome: CHR12: 102139274-102224645
Locus: 12q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNPTA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNPTAB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping