GNPI FISH Probe
The GNPI FISH probe is designed to hybridize to the GNPI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPI-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GPI-20-RE | 20 (40 μL) | 200 μL |  |
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| GPI-20-GO | 20 (40 μL) | 200 μL |  |
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| GPI-20-GR | 20 (40 μL) | 200 μL |  |
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| GPI-20-AQ | 20 (40 μL) | 200 μL |  |
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| GPI-20-DIG | 20 (40 μL) | 200 μL |  |
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| GPI-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: GPI
Gene Name: Glucose-6-phosphate Isomerase
Chromosome: CHR19: 34855644-34893318
Locus: 19q13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNPI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GPI-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping