GNL3L Break Apart FISH Probe
Empire Genomics’ GNL3L Break Apart FISH Probe is designed to flank the GNL3L gene and is typically used for detecting GNL3L rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNL3LBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-GORE | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-GROR | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-REGO | 20 (40 μL) | 200 μL |
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| GNL3LBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic cognitive disability. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: HUWE1
Gene Name: HECT, UBA And WWE Domain Containing 1, E3 Ubiquitin Protein Ligase
Chromosome: CHRX: 53559062-53713673
Locus: Xp11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNL3L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HUWE1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping