GNE Break Apart FISH Probe
Empire Genomics’ GNE Break Apart FISH Probe is designed to flank the GNE gene and is typically used for detecting GNE rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNEBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNEBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GNEBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GNEBA-20-GORE | 20 (40 μL) | 200 μL |
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| GNEBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GNEBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GNEBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GNEBA-20-REGO | 20 (40 μL) | 200 μL |
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| GNEBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GNE
Gene Name: Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine Kinase
Chromosome: CHR9: 36214438-36277053
Locus: 9p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNE-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping