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GNE FISH Probe

The GNE FISH probe is designed to hybridize to the GNE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GNE-20-OR  (Standard Design) 20 (40 μL) 200 μL
GNE-20-RE 20 (40 μL) 200 μL
GNE-20-GO 20 (40 μL) 200 μL
GNE-20-GR 20 (40 μL) 200 μL
GNE-20-AQ 20 (40 μL) 200 μL
GNE-20-DIG 20 (40 μL) 200 μL
GNE-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: GNE

Gene Name: Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine Kinase

Chromosome: CHR9: 36214438-36277053

Locus: 9p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GNE FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GNE-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping