GNB3 Break Apart FISH Probe
Empire Genomics’ GNB3 Break Apart FISH Probe is designed to flank the GNB3 gene and is typically used for detecting GNB3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNB3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNB3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| GNB3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| GNB3BA-20-GORE | 20 (40 μL) | 200 μL |
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| GNB3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| GNB3BA-20-GROR | 20 (40 μL) | 200 μL |
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| GNB3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| GNB3BA-20-REGO | 20 (40 μL) | 200 μL |
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| GNB3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: GNB3
Gene Name: G Protein Subunit Beta 3
Chromosome: CHR12: 6949374-6956557
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNB3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping