GNB3 FISH Probe
The GNB3 FISH probe is designed to hybridize to the GNB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNB3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GNB3-20-RE | 20 (40 μL) | 200 μL |  |
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| GNB3-20-GO | 20 (40 μL) | 200 μL |  |
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| GNB3-20-GR | 20 (40 μL) | 200 μL |  |
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| GNB3-20-AQ | 20 (40 μL) | 200 μL |  |
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| GNB3-20-DIG | 20 (40 μL) | 200 μL |  |
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| GNB3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: GNB3
Gene Name: G Protein Subunit Beta 3
Chromosome: CHR12: 6949374-6956557
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNB3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping