SEARCH OUR PRODUCT CATALOG

GNB3 FISH Probe

The GNB3 FISH probe is designed to hybridize to the GNB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GNB3-20-OR  (Standard Design) 20 (40 μL) 200 μL
GNB3-20-RE 20 (40 μL) 200 μL
GNB3-20-GO 20 (40 μL) 200 μL
GNB3-20-GR 20 (40 μL) 200 μL
GNB3-20-AQ 20 (40 μL) 200 μL
GNB3-20-DIG 20 (40 μL) 200 μL
GNB3-20-BIO 20 (40 μL) 200 μL

Gene Summary

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]

Gene Details

Gene Symbol: GNB3

Gene Name: G Protein Subunit Beta 3

Chromosome: CHR12: 6949374-6956557

Locus: 12p13.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GNB3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GNB3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping