GM FISH Probe
The GM FISH probe is designed to hybridize to the GM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GMDS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-RE | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-GO | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-GR | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-AQ | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-DIG | 20 (40 μL) | 200 μL |  |
|
| GMDS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]
Gene Details
Gene Symbol: GMDS
Gene Name: GDP-mannose 4,6-dehydratase
Chromosome: CHR6: 1624040-2245846
Locus: 6p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GMDS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping