GLP-1R FISH Probe
The GLP-1R FISH probe is designed to hybridize to the GLP-1R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLP1R-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-RE | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-GO | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-GR | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-AQ | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-DIG | 20 (40 μL) | 200 μL |  |
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| GLP1R-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: GLP1R
Gene Name: Glucagon Like Peptide 1 Receptor
Chromosome: CHR6: 39016556-39055520
Locus: 6p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GLP-1R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLP1R-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping