GLIS2 Break Apart FISH Probe
Empire Genomics’ GLIS2 Break Apart FISH Probe is designed to flank the GLIS2 gene and is typically used for detecting GLIS2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLIS2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| GLIS2BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: GLIS2
Gene Name: GLIS Family Zinc Finger 2
Chromosome: CHR16: 4382224-4389598
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GLIS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLIS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping