GLIS2 FISH Probe
The GLIS2 FISH probe is designed to hybridize to the GLIS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLIS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-RE | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-GO | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-GR | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GLIS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: GLIS2
Gene Name: GLIS Family Zinc Finger 2
Chromosome: CHR16: 4382224-4389598
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GLIS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLIS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping