GIRK-1 FISH Probe
The GIRK-1 FISH probe is designed to hybridize to the GIRK-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNJ3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNJ3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: KCNJ3
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 3
Chromosome: CHR2: 155555092-155713014
Locus: 2q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GIRK-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNJ3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping