GHBP FISH Probe
The GHBP FISH probe is designed to hybridize to the GHBP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GHR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GHR-20-RE | 20 (40 μL) | 200 μL |  |
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| GHR-20-GO | 20 (40 μL) | 200 μL |  |
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| GHR-20-GR | 20 (40 μL) | 200 μL |  |
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| GHR-20-AQ | 20 (40 μL) | 200 μL |  |
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| GHR-20-DIG | 20 (40 μL) | 200 μL |  |
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| GHR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
Gene Details
Gene Symbol: GHR
Gene Name: Growth Hormone Receptor
Chromosome: CHR5: 42423876-42721980
Locus: 5p13.1-p12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GHBP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GHR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping