GGCX Break Apart FISH Probe
Empire Genomics’ GGCX Break Apart FISH Probe is designed to flank the GGCX gene and is typically used for detecting GGCX rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GGCXBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GGCXBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GGCXBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GGCXBA-20-GORE | 20 (40 μL) | 200 μL |
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| GGCXBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GGCXBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GGCXBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GGCXBA-20-REGO | 20 (40 μL) | 200 μL |
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| GGCXBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: GGCX
Gene Name: Gamma-glutamyl Carboxylase
Chromosome: CHR2: 85771977-85788657
Locus: 2p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GGCX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GGCX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping