GGC FISH Probe
The GGC FISH probe is designed to hybridize to the GGC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GGCX-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GGCX-20-RE | 20 (40 μL) | 200 μL |  |
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| GGCX-20-GO | 20 (40 μL) | 200 μL |  |
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| GGCX-20-GR | 20 (40 μL) | 200 μL |  |
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| GGCX-20-AQ | 20 (40 μL) | 200 μL |  |
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| GGCX-20-DIG | 20 (40 μL) | 200 μL |  |
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| GGCX-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: GGCX
Gene Name: Gamma-glutamyl Carboxylase
Chromosome: CHR2: 85771977-85788657
Locus: 2p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GGC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GGCX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping